Protein Molecular Weight Markers
ABclonal Technology Rad23B Rabbit pAb
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
ABclonal Technology MTHFR Rabbit pAb
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
ABclonal Technology RBM25 Rabbit pAb
Enables mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome and regulation of apoptotic process. Located in nuclear speck.
ABclonal Technology MS4A7 Rabbit pAb
This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Meso Scale Discovery PhosphoThr231/Tau TTL20 Plate
The Meso Scale Discovery Phospho-Thr231/Total Tau Kit is a multiplex immunoassay kit that allows for the simultaneous measurement of phosphorylated Thr231 tau and total tau in biological samples such as CSF serum plasma cell lysates and brain homogenates The kit contains a 96-well plate coated with capture antibodies specific for phosphorylated Thr231 tau and total tau It utilizes MSD s electrochemiluminescence detection technology to provide sensitive and accurate quantification of both analytes from a single small sample volume The kit includes all necessary reagents and can process up to 80 samples in duplicate It is suitable for studying Alzheimer s disease and other tauopathies
ABclonal Technology TCEA1 Rabbit pAb
Predicted to enable DNA binding activity, translation elongation factor activity, and zinc ion binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within erythrocyte differentiation and positive regulation of transcription, DNA-templated. Located in nucleolus and nucleoplasm. Part of transcription factor TFIID complex.
Abcam Prestained Protein Ladder - E x tra broad molecular weight (6.5 - 270 kDa), 500UL
Prestained Protein Ladder ab234592 is a three-color protein standard with 10 pre-stained proteins covering a range of MW from 6.5-270 kDa.
The product is subject to the following: Abcam Restricted Use Statement
Biolegend PE anti-RPS6 Phospho Ser235/Se
PE anti-RPS6 Phospho (Ser235/Ser236) [A17020B]; Isotype: Mouse IgG1, κ; Reactivity: Human, Mouse; Apps: ICFC; Size: 25 tests
ABclonal Technology KIF13A Rabbit pAb
This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants.
ABclonal Technology DNTTIP2 Rabbit pAb
This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a potential biomarker for chronic obstructive pulmonary disease.